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Vanillin is considered a flavoring and fragrance substance with a pleasant vanilla note. The frequency of sensitization to vanillin is considered rare and the sensitization potency is considered low. In an illustrative risk assessment of cosmetic products containing vanillin, 0.5% vanillin was classified as safe. In Better Balm 0.33% vanillin was used, in Hypnotic Hues 0.16% vanillin was used(1).
(1) Gautier, F., Vandecasteele, H. A., Tourneix, F., van Vliet, E., Alépée, N., & Bury, D. (2023). Skin sensitization prediction using read-across, an illustrative next generation risk assessment (NGRA) case study for vanillin. Regulatory Toxicology and Pharmacology, 143, 105458.