Dimethyl isosorbide is a solvent that is used to improve the penetration of active ingredients into the skin due to its high penetration power. This can improve the effectiveness of the various ingredients(1).
(1) Zhang, Y., Kung, C. P., Iliopoulos, F., Sil, B. C., Hadgraft, J., & Lane, M. E. (2021). Dermal Delivery of Niacinamide-In Vivo Studies. Pharmaceutics, 13(5), 726. https://doi.org/10.3390/pharmaceutics13050726
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